Evidence Skincare (ESK) skin care products are formulated based on scientific studies that are peer-reviewed and published in major medical journals.

We only use ingredients and formulations which have been proven repeatedly in independent clinical trials to reduce the signs of aging, protect, smooth and nourish your skin, so you can put your best face forward.

The face creams and serums are pH balanced and use the exact ingredients that have shown to work – not the cheaper, less effective versions.

The result is an evidence-based skin care range that works, without the hype. You’ll see the difference. It’s skin care that simply works.

Retinal

Vitamin A

Retinal - Vitamin A

Retinal is the number 1 “must have ingredient” in any skin care regime. “Rewinds the clock on skin aging” and results in increased skin elasticity and reduces wrinkles, fine lines and pigmentation. Also effective in managing acne.

Vitamin A has the most and strongest evidence for reducing the signs of skin aging1. It has been shown to stimulate skin cell growth and collagen production2. Retinal is the most effective and least irritating from of Vitamin A1 (Other commonly used forms of Vitamin A including Retinol and Retinyl Palmitate have weak or no evidence). It reduces the appearance of fine lines and pigmentation and increases skin elasticity and is also useful in managing acne3

(1) Rivers 2008, Babamiri 2009, Mukherjee 2006, Sorg 2006, Didierjean 1999, Boisnic 1999
(2) Diridollou 1999, Creidi 1998, Fluhr 1999, Boisnic 1999
(3) Dreno 2005, Dreno 2009, Tran 2005

Niacinamide

Vitamin B3

Niacinamide - Vitamin B3

Reduces pigmentation and improves skin barrier function

An Anti-Oxidant, assists in repair of cell DNA. Improves skin barrier function (1) (decreases moisture loss), increases skin elasticity (2)and reduces pigmentation and skin yellowing (3).

(1) Ghering 2004, Crowther 2008, Christman 2012
(2) Bisset 2005, Kawada 2008
(3) Hakozaki 2002, Bisset 2004

L-Ascoric Acid

Vitamin C

L-Ascorbic Acid - Vitamin C

Protects and repairs damage from the sun – Reduces wrinkles, skin roughness, and pigmentation

An anti-oxidant, effective improving protection from and repair of sun induced premature aging1. It reduces wrinkles2, fine lines, skin roughness and pigmentation3. L-Ascorbic acid is naturally unstable and must be formulated in an oil base in order to delay oxidisation. Stabilised forms of Vitamin C are often used for convenience, however they have weak or no evidence4.

(1) Humbert 2003, Burke 2007, Aguilera 2012, Darr 1996, Lin 2003, Alexander 2012
(2) Raschke 2004, Farris 2005
(3) Xu 2012
(4) Campos 2008, Tsai 2012

Tocopherol

Vitamin E

Tocopherol - Vitamin E

Enhances the effectiveness of Vitamin C

The primary evidence for Tocopherol (Vitamin E) is when used in combination with Vitamin C. The combination is synergistic in protection from the sun’s UV radiation1
(1) Darr 1996, Lin 2003, Aguillera 2012, Burke 2007, Alexander 2012

Glycolic and Lactic Acid

Alpha Hydroxy Acids

Glycolic and Lactic Acid - Alpha Hydroxy acids

Exfoliates and smooths the skin

Improves skin texture and tone (1) through exfoliation. Helps remove dead skin cells on the surface and promotes skin cell growth (2).

(1) Kornhauser 2010, Stiller 1996
(2) Kim 1998, Newman 1996

4-n-butylresorcinol

Tyrosinase inhibitor

4-n-butylresorcinol

Reduces hyperpigmentation, for a lighter more even skin tone

Effectively targets hyperpigmentation and age spots. 4-n-butylresorcinol is a non-cytotoxic (1) highly effective tyrosinase inbitor (2)making it both effective (3), non-irritating (4) and safe for continuous long term use

(1) Okubo 1995
(2) Kolbe 2012
(3) Kim 2005, Shin 2014, Khemis 2007
(4) Huh 2010, Shin 2014